transforminggrowthfactor-β相关论文
目的:探讨干扰小RNA(siRNA)下调瘦素(leptin)的表达对体外培养的人病理性瘢痕成纤维细胞增殖能力及转化生长因子-βn 1(TGF-......
Transactivation of the TIEG1 confers growth inhibition of transforming growth factor-β-susceptible h
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The expression dynamics of transforming growth factor-β/Smad signaling in the liver fibrosis experim
Liver fibrosis is a hallmark of clonorchiasis suffered by millions people in Eastern Asian countries.However,little is k......
Transforming growth factor beta 1 induced differentiation of Telomerase-Immortalized swine umbilical
Swine umbilicus veins were isolated in sterile, 0.1% collagenase I was poured into umbilicus vein to digest, primary swi......
Blocking the Function of Inflammatory Cytokines and Mediators by Using IL-10 and TGF-β:A Potential B
The debilitating effects of lower back pain are a major health issue worldwide.A variety of factors contribute to this, ......
Dysregulated miR-127-5p contributes to extracellular matrix degradation and activation of TGF-β by t
Intervertebral disc degeneration(IDD)is associated with extracellular matrix(ECM)degradation.Dysregulated expression of ......
Targeted inhibition of TGF-β and IL-6/JAK2/Stat3pathways prohibit lung cancer growth promoted by bon
目的 Tumor microenviroment myofibroblasts(MFs)play an important role in the development and progression of lung cancerth......
Protection against acute radiation-induced lung injury:a novel role for the anti-angiogenic agent en
Radiotherapy is commonly used to treat thoracic malignancies but often causes severe lung injury.Currently there are no ......
Benzalkonium chloride induces subconjunctival fibrosis through the COX-2-modulated activation of a T
PURPOSE The purpose is to investigate the mechanism of subconjunctival fibrosis caused by benzalkonium chloride (BAC),wh......
Compound Astragalus and Salvia miltiorrhiza extract inhibits hepatocarcinogenesis via modulating TGF
Compound Astragalus and Salvia miltiorrhiza extract (CASE) is a Chinese herbal formula made up of astragalosides, astrag......
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Effect of low-molecular-weight heparin and urokinase on pulmonary arteries involved in pulmonary emb
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增生性玻璃体视网膜病变(proliferative vitreoretinopathy,PVR)是引起视网膜脱离手术失败及复发的常见原因,其病理生理机制复杂。本......
目的研究转化生长因子β1(trαnsforminggrowthfαctor—β1,TGFβl)、缺氧诱导因子一1α(hypoxiαinduciblefαctor—1β,HIF—1α)在唾......
目的探讨芍药苷对人神经胶质瘤U87细胞上皮间质转化和迁移侵袭的作用及其分子机制。方法不同浓度芍药苷分别加入培养基中处理胶质......
Neuron-like differentiation of adult rat bone marrow stromal cells induced by transforming growth fa
BACKGROUND: It has been demonstrated that transforming growth factor-β (TGF-β) and brain-derived neurotrophic factor (......
糖尿病肾病(DN)是糖尿病最为严重的并发症之一,严重威胁人类的健康,细胞因子的激活是病变形成的直接机制.细胞因子间相互影响、相......
转化生长因子β(TGF-β)是一种多功能细胞因子,在组织稳态和肿瘤进展中发挥着关键作用.TGF-β是一种强有力的免疫抑制因子,可通过......
转化生长因子β(TGF-β)家族是一个有着多效性的细胞因子,具有调节细胞的增殖、分化、迁移、生存等功能.近年来具有免疫抑制功能的......
转化生长因子-β(TGF-β)对角膜基质瘢痕形成具有极其重要的生物学效应,而且是导致细胞外基质(ECM)异常沉积及胶原纤维结构异常的......
晶状体是重要的屈光间质,其透明性的维持主要依赖晶状体上皮细胞(LECs).LECs的正常发育、增生、分化和凋亡主要依靠细胞因子及信号......
目的 探讨Rho/ROCK信号通路是否参与了TGF-β1诱导的尿道瘢痕成纤维细胞表型转化及细胞外基质过度合成.方法 进行原代培养人尿道瘢......
目的探讨特发性血小板减少性紫癜(idiopathic thrombocytopenic purpura ,ITP)患者血小板生成调控因子血小板生成素(Thrombopoietin,......
目的观察藏药湿生扁蕾对溃疡性结肠炎肠纤维化结构与转化生长因子β(TGF-β)表达的影响。方法按照体重将造模后大鼠随机分为5组,每组......
Tetrandrine inhibits activation of rat hepatic stellate cells in vitro via transforming growth facto
AIM: To investigate the effect of various concentrations of tetrandrine on activation of quiescent rat hepatic stellate ......
Side Population Cells in Human Gallbladder Cancer Cell Line GBC-SD Regulated by TGF-β-induced Epithe
Mounting evidence has shown that side population (SP) cells are enriched for cancer stem cells (CSCs) responsible for ca......
Connection between inflammation and carcinogenesis in gastrointestinal tract: Focus on TGF-β signali
Inflammation is a primary defense process against various extracellular stimuli, such as viruses, pathogens, foods, and ......
目的 探讨强直性脊柱炎(ankylosing spondylitis,AS)患者外周血中CD4+调节性T细胞(regulatory T cells,Treg)的表达、功能及意义.......
目的:检测糖尿病伴有高白蛋白尿患者尿中βig-h3的含量,以及用尿中βig-h3含量评估糖尿病肾病严重程度的可行性。方法采用酶联免疫法......
Survival from burn injury has improved considerably over the past two decades such that the quality of life of the victi......